Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

BACKGROUND:

Increasing evidence indicates that the interaction between the CXC chemokine receptor-4 (CXCR4) and its ligand CXCL12 is critical in the process of metastasis that accounts for more than 90% of cancer-related deaths.

Molecular Cancer ARCHIVE Non-Small Cell Lung Cancer Kidney Cancer Head and Neck Cancer Liver Cancer