Computational Biology Model of ETP-ALL Used to Accurately Classify ETP-ALL Vs Non ETP-ALL Patients with Genomic Input

Background: Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is an aggressive hematological malignancy with poor prognosis after chemotherapy compared to other ALLs. ETP-ALL cases typically display a high burden of chromosomal copy number variations (CNVs) and myeloid gene mutations.

Blood Journal 2017